POLYPHARMACY INDUCED DRUG INTERACTIONS, ADVERSE DRUG REACTIONS ( ADR) AND MEDICATION ERRORS IN TERTIARY CARE SOUTH INDIAN HOSPITAL
By: Siddarama, R
.
Contributor(s): Naidu, Bharath J.
Publisher: M P Innovare Academic Sciences Pvt Ltd 2019Edition: Vol.11(2).Description: 88-93p.Subject(s): PHARMACEUTICSOnline resources: Click here
In:
International journal of pharmacy and pharmaceutical scienceSummary: Objective:
To study the pattern of drug interactions (DI)
in our hospital and to identify whether it is associated with polypharmacy. To determine
the level of severity of potential drug
-drug interactions (PDDI
), to detect, monitor and prevention of ADRs in the hospitalized patients and to
identify the medication
errors (
ME).
Method
s:
A prospective interventional study was conducted in a 300 bedded tertiary care South Indian hospital for a period of 6 mo
. P
rescriptions
were
analysed
for PDDI using Micromedex software 2.2
. The causality and
severity of ADRs were assessed by using Nar
anjo’s, WHO UMC Scales and
Hart wigs se
verity scales. ME
was
identified by review of patient drug charts.
Result
s:
Total 190 prescriptions were analy
zed
, in which 1028 drug interactions were seen. Out of which 718 were DDI, 198 DFI, 100 DEI
, and
12
DTI were observed.
More
number of DI
was
seen in
cardiovascular drugs, antibiotics followed by antacids and antiulcer agents. A total of 52 ADRs
were identified in 43 patients. Diuretics, cardiovascular drugs were associated with a
higher
incidence of ADRs followed by Anti
-Diabetic agents. 58
ME
was seen in 190 prescription
s, among them omission error, prescribing errors and
Wrong dose error
was
seen
.
Conclusio
n:
Clinical pharmacist plays a potential role in the
health
care system in assisting the physician i.e.
modifying the number of drugs taken,
number of doses taken, medication adherence, identification of drug interactions, preventing, monitoring and detection of ADR
s and identifying the
medication errors
| Item type | Current location | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|
Articles Abstract Database
|
School of Pharmacy Archieval Section | Not for loan | 2020893 |
Objective:
To study the pattern of drug interactions (DI)
in our hospital and to identify whether it is associated with polypharmacy. To determine
the level of severity of potential drug
-drug interactions (PDDI
), to detect, monitor and prevention of ADRs in the hospitalized patients and to
identify the medication
errors (
ME).
Method
s:
A prospective interventional study was conducted in a 300 bedded tertiary care South Indian hospital for a period of 6 mo
. P
rescriptions
were
analysed
for PDDI using Micromedex software 2.2
. The causality and
severity of ADRs were assessed by using Nar
anjo’s, WHO UMC Scales and
Hart wigs se
verity scales. ME
was
identified by review of patient drug charts.
Result
s:
Total 190 prescriptions were analy
zed
, in which 1028 drug interactions were seen. Out of which 718 were DDI, 198 DFI, 100 DEI
, and
12
DTI were observed.
More
number of DI
was
seen in
cardiovascular drugs, antibiotics followed by antacids and antiulcer agents. A total of 52 ADRs
were identified in 43 patients. Diuretics, cardiovascular drugs were associated with a
higher
incidence of ADRs followed by Anti
-Diabetic agents. 58
ME
was seen in 190 prescription
s, among them omission error, prescribing errors and
Wrong dose error
was
seen
.
Conclusio
n:
Clinical pharmacist plays a potential role in the
health
care system in assisting the physician i.e.
modifying the number of drugs taken,
number of doses taken, medication adherence, identification of drug interactions, preventing, monitoring and detection of ADR
s and identifying the
medication errors
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